Rhonda delves into NAD+: its importance for aging, its decline as we age, and popular NAD+ enhancers like nicotinamide riboside and nicotinamide mononucleotide. NAD+ is vital for survival, with small dietary contributions, but the body mainly recycles it. Everyday life and aging reduce NAD+, leading to metabolic and mitochondrial issues, as well as age-related problems like increased DNA damage. Exercise, fasting, and NAD+ precursors like NR and NMN can boost levels, mostly from animal studies. However, their long-term effectiveness and safety in humans remain uncertain
NAD+ in Aging: The Roles of NR and NMN