It’s a great article, but please take it with a grain of salt. I believe telomeres are a product of aging, not aging itself.
Bill Andrews summarizes in 19 minutes his research on telomeres, aging, and the cure for aging.
Dr. Bill Andrews is a scientist and researcher known for his work in the field of telomere biology and aging. He has studied telomeres, which are protective caps on the ends of chromosomes, and their role in aging. Andrews is a proponent of telomere lengthening as a potential way to extend the human lifespan.
The video, originally released by Bill Andrews in February 2022, covers the following topics:
- 1) info about telomere shortening and its impact on aging.
- 2) Practical proposals to cure aging based on two approaches to stop telomere shortening and enlarge them.
- 3) Explanation of why telomere lengthening is suitable and fundamental to cure aging, demystifying the assumption that telomere lengthening causes cancer.
Based on diverse research on this topic, my take is that Telomeres are not the cause of aging, but they are a related factor. Telomeres are the protective caps on the ends of our chromosomes, and they naturally shorten as cells divide over time. This shortening is considered a consequence or output of the aging process (keywords here are consequence or output).
As telomeres shorten, it can lead to cellular senescence (a state in which cells can no longer divide), DNA damage, and an increased risk of various age-related diseases. While telomere shortening is associated with aging, it is just one of many factors contributing to the complex aging process. Other factors, such as genetic, environmental, and lifestyle factors, also play significant roles in determining how and why we age.
To me, the questions in mind are:
- What causes telomere to shorten
- How are other aging factors related?
- Why do cells stop reproducing or replicating?
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