Aging Research and development
When tumor suppressor genes mutate, their products no longer inhibit the cell cycle or promote apoptosis (the death of cells occurs as a regular and controlled part of an organism’s growth or development). Therefore, these mutations can be called “loss-of-function,”
Epigenetics has emerged as a promising frontier in the quest to effectively treat various human diseases. It involves modifications to DNA or DNA-associated proteins, like histones, without altering the DNA sequence itself. These modifications play a pivotal role in determining
DNA methylation and histone acetylation are two epigenetic mechanisms that regulate gene expression. Methylation is adding a methyl group to a cytosine nucleotide in DNA. At the same time, acetylation adds an acetyl group to a lysine residue in a
Abstract Background Tree nuts and peanuts (henceforth, nuts) are nutrient-dense foods rich in neuroprotective components; thus, their consumption could benefit cognitive health. However, evidence to date is limited and inconsistent regarding the potential benefits of nuts for cognitive function. Objective To prospectively
Abstract Hair graying is a common sign of aging resulting from complex regulation of melanogenesis. Currently, there is no medical treatment available for hair repigmentation. In this article, we review the literature on medication-induced hair repigmentation, discuss the potential mechanisms
Hair color is determined by the amount of a pigment called melanin. An abundance of one type of melanin, called eumelanin, gives people black or brown hair. An abundance of another pigment, called pheomelanin, gives people red hair. Hair color